While effective for short-term use, prolonged or high-dose use of Ativan can lead to physical dependence, making withdrawal a challenging and sometimes dangerous process. Symptoms can be both physical and psychological, ranging from increased anxiety and insomnia to severe panic attacks and seizures.
While the withdrawal process is complex, understanding what to expect and how to manage symptoms can help you navigate this trying time.
What is Ativan?
Ativan, the brand name for lorazepam, is a benzodiazepine commonly prescribed to treat anxiety, panic disorders, insomnia, and seizures. While effective in providing short-term relief, Ativan use, particularly long-term or at high doses, can lead to physical dependence.
Lorazepam, like other benzodiazepines, enhances the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits nerve activity in the brain. By increasing GABA activity, Ativan calms the central nervous system, leading to reduced anxiety, relaxation, and sedation. Although this prescriptive drug can help people with anxiety issues, Ativan can also be addictive if you become too dependent on it.
Over time, with regular Ativan use, the brain adapts to the increased GABA activity. It reduces its own natural GABA production and the number of GABA receptors. This adaptation means that the brain relies on Ativan to maintain a normal level of calmness and function.
Understanding Ativan Withdrawal
When Ativan use is stopped or significantly reduced, the brain is suddenly deprived of the enhanced GABA activity it has grown accustomed to. This disruption leads to a state of imbalance in the central nervous system, triggering a cascade of withdrawal symptoms. The severity and duration of these symptoms depend on several factors, including the dosage, duration of use, and individual physiology.
When you decide to stop taking Ativan, it’s crucial to understand the withdrawal process and potential symptoms.
Withdrawal symptoms can begin within 24 hours after your last dose, with early signs like increased anxiety, irritability, and insomnia.
Acute withdrawal syndrome occurs when a person abruptly stops or rapidly reduces use after developing physical dependence. Symptoms typically begin within 8 to 12 hours and peak around 2 to 4 days after the last dose.
The severity and duration of these withdrawal symptoms often depend on the dosage and length of your Ativan use. Higher doses and prolonged use can result in more intense symptoms.
It’s essential to seek medical supervision during withdrawal due to the risk of dangerous complications, such as seizures and severe psychological distress. Read more about our Outpatient Treatment for Ativan Addiction in Minneapolis..
Physical Symptoms of Ativan Withdrawal
Physical symptoms are a significant part of the Ativan withdrawal process. Within 24-48 hours of your last dose, you may start experiencing headaches, sweating, and tremors as physical withdrawal symptoms manifest.
During the acute phase, which usually lasts 10-14 days, expect an increased heart rate, palpitations, and elevated blood pressure. Nausea and abdominal cramps are common gastrointestinal issues you might face while withdrawing from Ativan.
Severe cases can trigger life-threatening symptoms like seizures and psychotic reactions, especially if you abruptly stop taking the medication.
Even after cessation, protracted withdrawal may cause lingering physical symptoms such as insomnia and persistent muscle tension for weeks or months.
Psychological Symptoms of Ativan Withdrawal
Severe anxiety, panic attacks, and heightened irritability can begin within 24-48 hours after your last dose. You may experience depressive symptoms, including feelings of hopelessness and sadness, which can persist throughout withdrawal.
Cognitive issues, such as confusion, concentration difficulties, and memory disturbances, can impact your daily functioning. Many individuals report increased sensitivity to sensory stimuli, exacerbating feelings of anxiety and discomfort.
Rebound anxiety and insomnia are common psychological symptoms that typically occur 2-3 days after acute withdrawal.

Ativan Withdrawal Timeline
You’ll likely notice early withdrawal symptoms within 24-48 hours of your last dose, which may include heightened anxiety and irritability.
The acute withdrawal phase typically kicks 3-4 days after stopping, peaking during the first week. This phase can last 10-14 days and is often marked by severe anxiety, panic attacks, and tremors.
Afterward, you might encounter rebound anxiety and insomnia for 2-3 days.
Protracted withdrawal symptoms, such as persistent anxiety, depression, and cognitive issues, can linger for weeks to months.
Keep in mind that factors like dosage and duration of use can impact the severity and duration of your withdrawal experience.
Managing the Withdrawal Symptoms
Gradual tapering under medical supervision is essential to minimize the severity of withdrawal symptoms and prevent complications like seizures. Your healthcare provider can customize a tapering schedule and provide supportive care based on your needs.
Expect acute withdrawal symptoms to peak within the first week, and be prepared for potential protracted symptoms lasting weeks or months.
Utilize mental health resources and therapy to cope with psychological symptoms, making your recovery more manageable.
Final Thoughts from Northwoods Haven Recovery
Ativan withdrawal can be a challenging and potentially dangerous process. At Northwoods Haven Recovery in Minneapolis, we offer a comprehensive Intensive Outpatient Program (IOP) tailored for Ativan (lorazepam) addiction treatment. Our outpatient approach provides structured therapy and support while allowing patients to maintain their daily routines, making it a flexible option for those seeking recovery. The program focuses on addressing both the physical and psychological aspects of addiction through counseling, group therapy, and relapse prevention strategies.